Hi @Komal-Sharma
I'm using Zoho mail service.
Mailbox setup is OK. I'm receiving emails/tickets:
$ php bin/console uvdesk:refresh-mailbox email@domain.com
1. Processing uvdesk mailbox configuration.
2. Opening imap stream...
3. IMAP stream opened.
4. Fetching Email collection since 08 March 2023.
5. Total fetched email -> 1
6. Starting to convert Emails into Tickets ->
=============================================
=============================================
Converting email 1 out of 1.
Mailbox refreshed successfully !!!
The issues is that I don't have any errors when I'm sending replies 

As explained, I also created a sample php script (using SwiftMail) and it's sending emails with the same credentials.
I noticed that there is a configuration on the .env file:
#
# For Gmail as a transport, use: "gmail://username:password@localhost"
# For a generic SMTP server, use: "smtp://localhost:25?encryption=&auth_mode="
# Delivery is disabled by default via "null://localhost"
MAILER_URL=null://localhost
#
Do I need to change this as well (althogh not mentioned in some of the HowTos)?
Kind regards,
A.