Does the following command not use swiftmailer normal email sending?

php bin/console swiftmailer:email:send

When using this with my configuration everything works using AWS SES so it doesn't make sense that I'd need to do anything special unless i need to reformat like 464 as you describe. I'll try to determine how to do that. The reference link you sent is fairly vague and I'm not a php developer so I'll play with this a bit more but so far (I'm guessing I just need to fix which fields are passed such as the sender), I keep getting failures when I clear cache so I'm concerned I'm breaking other things.

I created a manual configuration similar to the one listed above by @Sanjeev. This works fine for sending on the command line

php bin/console swiftmailer:email: send

However I get no emails when using the UVdesk interface and I'm not seeing anything in the logs that tells me what's going on. Amazon Web Services (AWS) Simple Email Server is a requirement for us to deploy customer-facing solutions, so using Gmail for outgoing email won't work for us. I'm guessing it is something simple i'm overlooking. I've read about AWS SES requiring base64, so perhaps there's a config i need to do to force this, though i wouldn't think that would be an issue since I can send email through swiftmailer just fine using the command line.